Daniel Dubois will face Trevor Bryan for the WBA Regular world title on June 11.
The Greenwich heavyweight’s bout in the States will be shown live on BT Sport.
Veteran American promoter Don King won the purse bid to stage the contest, ensuring that Bryan will have home advantage for his defence of the belt.
Dubois, 24, has landed his shot despite no notable victories since he quit in the 10th round against Joe Joyce in November 2020.
Since then he has had easy stoppage victories over Joe Cusumano in Cleveland in August. He previously won the WBA Interim belt with a second round demolition of Bogdan Dinu in Telford.
Frank Warren, who promotes Dubois, said: “I am thrilled that Daniel is getting his big opportunity to fight for a world championship belt.
“He has had to bide his time and be a little bit patient because there was always the risk of him being bypassed if he took another fight in the interim.
“Now his time has come and winning this fight will open all sorts of doors. A new generation of top heavyweights are closing in on the current kings of the division and Daniel, along with Joe Joyce, is leading the charge.
“Bryan isn’t a household name but there can be no room for complacency. He is unbeaten with a more than respectable knockout ratio, so Daniel will need to be on his guard and on his game in Miami.”