Despite, or perhaps because of, their prowess in European competition, this remains a trophy which the Spanish giants have never lifted.
Xavi is out to end that unwanted run by guiding Barcelona to the only piece of silverware left available to them this campaign.
Sevilla and Real Madrid have been dispatched in recent weeks by the resurgent Blaugrana, who defeated Napoli and Galatasaray to reach this stage. Frankfurt overcame Spanish opposition in the last-16, downing Real Betis.
With kick-off at 8pm BST, here are all the details for tuning in…
Where to watch Eintracht Frankfurt vs FC Barcelona
TV channel: The match will be televised on BT Sport Extra 1, with coverage beginning shortly before kick-off.
Live stream: BT Sport subscribers will be able to watch the match online via the BT Sport website or app.
Live blog: You can follow all the action via Standard Sport’s live blog.