The Portuguese side have already knocked out Barcelona and Ajax in this year’s competition but the Reds will fancy their chances at Estadio da Luz.
Trent Alexander-Arnold was deemed “fully fit” by Jurgen Klopp for Saturday’s win over Watford yet remained on the bench having only just returned from a hamstring injury.
Sadio Mane and Luis Diaz were named on the bench for that Premier League game after returning from international duty and could return to face Benfica.
Naby Keita is back in training after a knee injury while Curtis Jones and Joel Matip have both shaken off knocks picked up against the Hornets.
Klopp said on Monday: “The full squad is available. Curtis had a little swelling, which disappeared overnight. Trent has now trained for four, five days so is ready as well.”
Predicted Liverpool XI: Alisson; Alexander-Arnold, Konate, Van Dijk, Robertson; Thiago, Fabinho, Henderson; Salah, Jota, Diaz.