With Ruben Dias ruled out of action for the next six weeks and United boasting a decent record at the Etihad Stadium in recent seasons, the outcome of Manchester derby could have a major say on deciding who sits atop the division at the end of the season.
As if a meeting between two of England’s biggest clubs from the same city needed more narrative, Liverpool are breathing down City’s necks and could take a huge advantage should United emerge victorious.
United, meanwhile, will be facing one of the traditional top six for the first time under Ralf Rangnick. Having been outplayed at Old Trafford in November while under previous management, they surely can’t be any worse this time around.
Here’s everything you need to know about where to watch the game.
Where to watch Manchester City vs Man United
TV channel: The game will be broadcast on Sky Sports Main Event, Sky Sports Premier League and Sky Sports Ultra HD.
Live stream: Sky Sports subscribers will be able to it through the Sky Go app.
LIVE coverage: Follow all of the action through Standard Sport’s dedicated match blog.