City blew Sporting away with a stunning display of firepower in Lisbon three weeks ago.
The confidence running through Guardiola’s free-scoring side will only have moved up a gear after that derby hammering of sorry United and it would take an upset of absolutely monumental proportions to deny them a place in the quarter-finals.
This is the trophy City so desperately crave and they will want to keep impressing as they progress deeper into the tournament. Another comprehensive victory beckons.
Man City to win, 3-0.
Early Sporting team news
For Sporting, the in-demand Joao Palhinha is a doubt along with Pedro Goncalves, while Matheus Nunes is suspended.
Man City team news
Pep Guardiola says City have just 14 players available for this second leg, with Kyle Walker still suspended in Europe – something his manager remains furious about – and Joao Cancelo out with illness.
The likes of Ruben Dias, Nathan Ake, Cole Palmer and Zack Steffen are also sidelined.
However, Guardiola will still be expected to make several changes to his starting XI, with a trip to Crystal Palace and FA Cup last-eight meeting with Southampton approaching quickly.
18-year-old defender Luke Mbete could make an appearance along with Oleksandr Zinchenko, while Kevin De Bruyne could be among those top names rested here.
How to watch tonight’s action
TV channel: Tonight’s game will be televised live on BT Sport 2 and BT Sport Ultimate, with coverage beginning at 7pm.
Live stream: BT Sport subscribers will also be able to watch the action unfold online via the BT Sport website or app.
LIVE coverage: You can also follow the match with Standard Sport’s dedicated match blog.
Good evening and welcome to Standard Sport’s LIVE match coverage of Sporting’s trip to Manchester City.
Kick-off from the Etihad Stadium is at 8pm GMT.