Stones limped off against Real Madrid in Tuesday’s Champions League thriller and it is currently touch and go as to whether or not he will be able to feature in the return leg this coming Wednesday.
Walker, meanwhile, is still suffering from an ankle problem.
With the semi-final away in Spain only days away, it seems reasonable to expect rotations.
Ilkay Gundogan, Nathan Ake, Raheem Sterling and Jack Grealish could all feasibly come into the side, while Joao Cancelo will return following his suspension in Europe.
This is a fine balancing act for City.
Any slip-up in the League could easily hand Liverpool the title but players need resting, with the Champions League surely the focus.
Manchester City XI (4-3-3): Ederson, Cancelo, Ake, Laporte, Zinchenko, Fernandinho, Gundogan, Silva, Sterling, Foden, Grealish
Injured: Walker, Stones
Date and time: 5.30pm on Saturday 29 April 2022
TV channel: Sky Sports