Sancho is set to remain absent for tonight’s Premier League visit of Brentford to Old Trafford due to tonsilitis, having also sat out Thursday’s 1-1 draw against Chelsea.
And Rangnick believes the England winger could stay on the sidelines for all of United’s final three outings this term.
“As it seems, Jadon might be out for the rest of the season with his tonsillitis so he will most likely be not available against Brentford,” the German said.
“Since the last game is another three weeks to go against Crystal Palace, but for the next two games I think it is unlikely.
“He definitely has an inflammation on his tonsils and has also had some high temperatures, that’s why he was not available for Chelsea and he almost certainly won’t be available for the next couple of games.
”So, hopefully, they can get hold of that inflammation and if the tonsils have to be taken out and removed, this can happen at the end of the season.”
Harry Maguire, Paul Pogba and Luke Shaw are all expected to remain out for United against Brentford, while there remain fitness doubts over Edinson Cavani and Aaron Wan-Bissaka.
Better news for Rangnick is that Fred is expected to be fit to return in midfield, though Jesse Lingard could be out again through personal reasons.
A number of United players will likely be playing their final home games for the club tonight, meanwhile, with their final two fixtures of the season coming away at Brighton and Crystal Palace respectively.
Predicted Manchester United XI: De Gea; Dalot, Varane, Lindelof, Telles; Fred, McTominay; Fernandes, Elanga, Rashford; Ronaldo.