The Prince of Wales and Camilla will step up to represent Her Majesty.
It is understood to be the first time Charles has represented his mother at the ancient royal event.
It will take place at St George’s Chapel, Windsor on 14 April.
The royal couple will be met by the Dean of Windsor, The Right Reverend David Conner KCVO and the Lord High Almoner, the Right Reverend Dr. John Inge.
Following the service, The Prince and The Duchess will proceed to the West Steps where an official photograph will be taken of Their Royal Highnesses and the Royal Maundy party.
It is understood the Queen was unable to commit that she would be able to attend.
The monarch attended a service commemorating the life of the Duke of Edinburgh last week with senior royals and a congregation of hundreds.
She has been carrying out virtual events and her other duties as head of state.
There have been four occasions where another MRF has attended in Her Majesty’s absence:
1954: The Lord High Almoner represented The Queen as Her Majesty was on a Commonwealth Tour
1960: Queen Elizabeth The Queen Mother represented The Queen as Prince Andrew was born in February
1964: The Princess Mary, Princes Royal, represented The Queen as Prince Edward was born in March
1970: Queen Elizabeth The Queen Mother, represented The Queen as Her Majesty was on tour in New Zealand
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